ADV - Care Pharmacy
195 Riviera Dr. Unit #2,Markham,Ontario
Tel: (905)948-1991

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Brand Name
Flovent
Common Name
fluticasone
How does this medication work? What will it do for me?

Fluticasone belongs to the class of medications called inhaled corticosteroids, which reduce symptoms and prevent asthma attacks by decreasing inflammation in the lungs and thereby opening the airways. When used regularly every day, inhaled fluticasone decreases the number and severity of asthma attacks. However, it will not relieve an asthma attack that has already started.

Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are being given this medication, speak to your doctor. Do not stop using this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to use this medication if their doctor has not prescribed it.

How should I use this medication?

The recommended regular daily dose of fluticasone inhalation is that which is the lowest required to control asthma symptoms. The full benefit of this medication may take 1 to 2 weeks or longer to achieve.

For the diskus only: The usual dose for children over 4 years of age is 50 µg or 100 µg twice daily (the number of inhalations varies depending on strength of medication used). Your doctor may tell you to adjust the dose of this medication in order to find one that helps control your asthma symptoms.

For the HFA inhaler and diskus: The usual dose for adults and adolescents over 16 years of age is 100 µg to 500 µg twice daily (the number of inhalations varies depending on strength of medication used). For people with severe asthma, higher doses up to 1,000 µg twice daily may be needed.

Inhaled fluticasone is used to prevent asthma attacks. It is not used to relieve an attack that has already started. For relief of an asthma attack that has already started, you should use another medication. If you do not have another medication to use for an attack or if you have any questions about this, check with your health care professional. If your doctor has asked you to use a "reliever" inhaler such as salbutamol or terbutaline with your fluticasone inhaler, you should use the reliever inhaler first, wait several minutes, and then use the fluticasone inhaler. The reliever medication will provide immediate relief of symptoms of asthma attack, while the fluticasone inhalation works to treat and control asthma regularly.

The HFA inhaler should be shaken well before use. In order to get the most medication into the lungs from the inhaled dose, ask your doctor or pharmacist about proper techniques for taking this medication.

Rinsing your mouth and gargling with water after each inhalation can help prevent hoarseness, throat irritation, and infection in the mouth caused by candidiasis (a type of yeast infection of the mouth; also known as "thrush"). If you have dentures, they should be cleansed after each dose.

Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.

It is important that this medication be used exactly as prescribed by your doctor. If you miss a dose, administer it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not administer a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

What form(s) does this medication come in?

Diskus

Each inhalation of the dry powder inhalation device delivers 50, 100, 250, or 500 µg of fluticasone propionate. It also contains lactose (milk sugar), including milk protein, which acts as the "carrier". FLOVENT DISKUS is a plastic inhaler device containing a foil strip with 60 blisters. Each blister contains 50, 100, 250, or 500 µg of the active ingredient fluticasone propionate.

Inhalation Aerosol

Each actuation of the pressurized metered-dose inhaler delivers: 50, 125, or 250 µg of fluticasone propionate suspended in propellant HFA-134a (1,1,1,2-tetrafluoroethane). This product does not contain chlorofluorocarbons (CFCs) as the propellant. The 50 µg strength of FLOVENT HFA inhalation aerosol is available in 120 dose containers. The 125 µg and 250 µg strengths of FLOVENT HFA inhalation aerosol are available in 60 and 120 dose containers. FLOVENT HFA inhalation aerosol is a pressurized metered-dose inhaler (MDI) consisting of an aluminum canister fitted with a metering valve. The 50 µg canister is fitted into the supplied peach actuator/adaptor. The 125 µg canister is fitted into the supplied orange actuator/adaptor. The 250 µg canister is fitted into the supplied red/brown actuator/adaptor. A dust cap is fitted over the actuator's mouthpiece when not in use.

Who should NOT take this medication?

Fluticasone should not be used by anyone who:

  • is allergic to fluticasone or to any of the ingredients of the medication
  • is allergic to milk or lactose (in the case of the diskus only)
  • has active or inactive untreated pulmonary tuberculosis
  • has moderate to severe bronchiectasis
  • has untreated fungal, bacterial, or viral infections
  • needs treatment for status asthmaticus or other acute asthma conditions
What side effects are possible with this medication?

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent. The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.

The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

  • cough
  • sore mouth and tongue

Although most of these side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

  • anxiety
  • skin bruising
  • swelling of face, lips, or eyelids
  • tightness in chest, difficulty breathing, or wheezing
  • white patches in mouth and throat
  • worsening of asthma

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.

Are there any other precautions or warnings for this medication?

Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.

Non-responsive asthma: Contact the doctor immediately if you experience episodes of asthma that are not responsive to bronchodilators (such as salbutamol or terbutaline) while using this medication. During such episodes, further treatment may be needed.

Oral hygiene: Adequate oral hygiene is very important in minimizing the overgrowth of microorganisms such as candidiasis (thrush). Proper oral hygiene includes rinsing your mouth with water after using the inhaler. Using a spacer device with the inhaler can greatly reduce how much medication stays in your mouth. Thrush infections, should they occur, may require treatment with appropriate antifungal therapy or the discontinuance of treatment with fluticasone, depending on the severity of the infections.

Stopping this medication: Do not stop this medication abruptly, as this may result in withdrawal symptoms associated with suppressed adrenal glands (e.g., stomach discomfort or pain, worsening of asthma). Your doctor will tell you to gradually lower the dose over a period of time in order to stop this medication properly.

Worsening of asthma: Increasing use of your bronchodilators (e.g., salbutamol) to control asthma symptoms is an indication that your asthma may be worsening. Sudden and progressive worsening in asthma control is potentially life-threatening, and consideration should be given to increasing the dose of fluticasone inhalation. Talk to your doctor or pharmacist to learn more about how to properly monitor for symptoms of worsening asthma.

Pregnancy: The safety of fluticasone for use during pregnancy has not been established. Potential benefits need to be weighed against risks, especially in the first trimester of pregnancy.

Breast-feeding: Corticosteroid medications such as fluticasone pass into breast milk. Although the amount that appears in breast milk would likely be low, the benefits of using this medication during pregnancy need to be weighed against risks.

Children: This medication is not recommended for use by children under 4 years of age.

What other drugs could interact with this medication?

There may be an interaction between fluticasone and any of the following:

  • acetylsalicylic acid (ASA)
  • ketoconazole
  • ritonavir

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

  • stop taking one of the medications,
  • change one of the medications to another,
  • change how you are taking one or both of the medications, or
  • leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.





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