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|How does this medication work? What will it do for me?|
Interferon beta-1b belongs to the group of medications known as immunomodulators. It is a form of a protein that is naturally made by our body's cells to fight infections and tumours. Interferon beta-1b is used to treat relapsing forms of multiple sclerosis (MS).
Multiple sclerosis (MS) is a chronic and disabling disease caused by the body's own defense system attacking and destroying the protective covering known as myelin that surrounds nerve fibres. Interferon beta-1b works by slowing down the attack of the body's defense cells on the nerves. Interferon beta-1b is used to reduce the frequency of exacerbations (worsening of symptoms) in people suffering with relapsing-remitting multiple sclerosis.
This medication is also used to delay the onset of MS in people who have experienced a single flare-up of symptoms and have changes that suggest MS in their magnetic resonance imaging (MRI) scans.
This medication can also be used to treat people with another type of MS known as SPMS (secondary progressive MS) who are still having relapses. In people with SPMS, the medication can decrease the frequency of relapses and reduce brain lesions seen on MRI scans.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are being given this medication, speak to your doctor. Do not stop using this medication without consulting your doctor.
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to use this medication if their doctor has not prescribed it.
|How should I use this medication?|
The recommended adult dose of interferon beta-1b is 0.25 mg (8 MIU) injected subcutaneously (under the skin) every other day. In some cases, the doctor may prescribe a lower dose (4 MIU every other day) for 2 weeks before increasing the dose to the recommended adult dose.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.
Interferon beta-1b is used with the guidance and supervision of a doctor. Your doctor or nurse may ask you to inject the medication at Return to Home Page once they have instructed you and are certain that you won't have any problems with doing it at Return to Home Page. Do not attempt to prepare or inject this medication on your own until you completely understand how to mix and inject a dose.
Use a different injection site for each dose. You should avoid injecting this medication into an area of skin that is sore, red, infected, or otherwise damaged. If you are having difficulty giving yourself injections, talk to your health care provider.
See the package insert for instructions on choosing the injection site, preparing the injection, and injecting the medication. Before mixing, interferon beta-1b should be kept at temperatures between 2°C and 25°C. Excursions between 25°C and 30°C are permitted as long as they do not exceed a maximum of 30 days. Do not freeze. After mixing, the vial or syringe containing the medication should be kept in a refrigerator and used within 3 hours.
Protect this medication from light, moisture, freezing and high temperatures. Keep this medication out of reach of children.
|What form(s) does this medication come in?|
Each single-use vial of lyophilized powder contains 0.3 mg (9.6 MIU) interferon beta-1b. Nonmedicinal ingredients: 15 mg albumin human USP and 15 mg mannitol USP. Each prefilled diluent syringe contains sodium chloride 0.54%.
|Who should NOT take this medication?|
Do not use this medication if you:
|What side effects are possible with this medication?|
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.
The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop taking the medication and seek immediate medical attention if any of the following occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.
|Are there any other precautions or warnings for this medication?|
Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
Blood counts: This medication can decrease the number of neutrophils (a type of white blood cell that helps fight infection) and platelets (which help your blood to clot). Your doctor will do blood tests to monitor this. If you notice any signs of infection (e.g., fever, chills, or sore throat) or unusual bleeding or bruising, contact your doctor immediately.
Depression: Depression has been reported by some people taking interferon medications. If you have a history of depression, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
If you have depression you should be closely monitored by your doctor. If symptoms of depression such as poor concentration, changes in weight, changes in sleep, decreased interest in activities, or thoughts of suicide occur while taking this medication contact yourdoctor as soon as possible.
Heart problems: This medication may worsen symptoms of heart disease. If you have heart disease such as angina, congestive heart failure, or arrhythmia you should discuss with your doctor how this medication may affect the medical condition, how the medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed. Contact your doctor as soon as possible if you develop symptoms of heart problems such as shortness of breath, chest pain, rapid heartbeat, or swollen ankles.
Liver damage: This medication may cause severe liver damage. Although rare, this side effect can be very serious. If you have a history of poor liver function, alcohol abuse, or active liver disease, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Your doctor will test your liver function regularly while you are taking this medication. Contact your doctor as soon as possible if you notice any of the signs of liver damage, including yellow eyes or skin, easy bruising of the skin, nausea and vomiting, itching, or abdominal pain.
Seizures: Some people have had seizures while taking this medication, including patients who have never had seizures before. It is not known whether the seizures were related to the effects of their MS, to the medication, or to the combination of both. If you have a seizure disorder, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed. If you have a seizure while taking this medication, you should call your doctor right away.
Thyroid problems: Some people taking this medication develop changes in the function of their thyroid. Symptoms of these changes include feeling cold or hot all the time, a change in weight (gain or loss) without a change in your diet or amount of exercise you get, or feeling emotional. Contact your doctor if you experience these symptoms.
Pregnancy: This medication should not be used during pregnancy. If you become pregnant while taking this medication, contact your doctor immediately. Women who may become pregnant should use effective contraception while taking this medication.
Breast-feeding: It is not known if interferon beta-1b passes into breast milk. If you are a breast-feeding mother and are taking this medication, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children and adolescents: The safety and effectiveness of using this medication have not been established for children and adolescents under 18 years of age.
|What other drugs could interact with this medication?|
Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
The contents of this site are for informational purposes only. Always seek the advice of your physician or other qualified healthcare provider regarding any questions you may have about a medical condition.
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